NanoKnife System
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NanoKnife System

A Unique Alternative to Thermal Ablation.

Since being introduced to US market in 2007, the NanoKnife System has been used in over 5,450 procedures.

A NanoKnife* procedure is an ablation procedure that involves the delivery of a series of high voltage direct current electrical pulses between two electrodes placed within a target area of tissue. The electrical pulses produce an electric field which induces electroporation on cells within the target area. Electroporation is a technique in which an electrical field is applied to cells in order to increase the permeability of the cell membranes through the formation of nanoscale defects in the lipid bilayer.

After delivering a sufficient number of high voltage pulses, the cells surrounding the electrodes will be irreversibly damaged. This mechanism which causes permanent cell damage is referred to as Irreversible Electroporation (IRE).

The NanoKnife System has been cleared by the FDA for the surgical ablation of soft tissue. It has not received clearance for the therapy or treatment of any specific disease or condition.

For more information on NanoKnife System, click here.

Important Risk Information

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Warren's Story

Being innovative is one thing, being part of a patient's...continuum of care, that's something that makes me get up every day and it's a powerful feeling.